In many body organs and beneath the skin, receptor nerve cells function as the initial site of pain. These receptor cells transmit signals to the spinal cord, which then transmits the signal to the brain whether you are ill, injured, or experiencing another kind of issue. Before they reach the brain, painkillers lessen or stop these signals. Anything that hurts might range from a little irritation, like a headache, to an immediate, intense pain, like kidney stones or the agony in the chest during a heart attack. Acute or subacute pain may be modest and transient or recent and severe. One of the most important medical issues is low back pain.
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